全文获取类型
收费全文 | 23183篇 |
免费 | 3332篇 |
国内免费 | 1177篇 |
专业分类
耳鼻咽喉 | 169篇 |
儿科学 | 384篇 |
妇产科学 | 257篇 |
基础医学 | 4468篇 |
口腔科学 | 550篇 |
临床医学 | 2026篇 |
内科学 | 5334篇 |
皮肤病学 | 622篇 |
神经病学 | 1458篇 |
特种医学 | 525篇 |
外国民族医学 | 13篇 |
外科学 | 1877篇 |
综合类 | 3029篇 |
现状与发展 | 5篇 |
预防医学 | 1141篇 |
眼科学 | 373篇 |
药学 | 1768篇 |
4篇 | |
中国医学 | 309篇 |
肿瘤学 | 3380篇 |
出版年
2024年 | 66篇 |
2023年 | 463篇 |
2022年 | 857篇 |
2021年 | 1314篇 |
2020年 | 1161篇 |
2019年 | 1208篇 |
2018年 | 1124篇 |
2017年 | 1044篇 |
2016年 | 1157篇 |
2015年 | 1233篇 |
2014年 | 1518篇 |
2013年 | 1501篇 |
2012年 | 1519篇 |
2011年 | 1626篇 |
2010年 | 1427篇 |
2009年 | 1341篇 |
2008年 | 1289篇 |
2007年 | 1138篇 |
2006年 | 1004篇 |
2005年 | 818篇 |
2004年 | 626篇 |
2003年 | 657篇 |
2002年 | 515篇 |
2001年 | 482篇 |
2000年 | 407篇 |
1999年 | 290篇 |
1998年 | 243篇 |
1997年 | 226篇 |
1996年 | 142篇 |
1995年 | 129篇 |
1994年 | 129篇 |
1993年 | 106篇 |
1992年 | 100篇 |
1991年 | 68篇 |
1990年 | 61篇 |
1989年 | 59篇 |
1988年 | 62篇 |
1987年 | 44篇 |
1986年 | 46篇 |
1985年 | 83篇 |
1984年 | 58篇 |
1983年 | 46篇 |
1982年 | 33篇 |
1981年 | 45篇 |
1980年 | 51篇 |
1979年 | 27篇 |
1978年 | 36篇 |
1977年 | 18篇 |
1976年 | 31篇 |
1975年 | 16篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
用基因工程重组的丙肝抗原包被于硝酸纤维素膜,建立了检测丙肝IgG抗体的斑点免疫渗滤法。与ELISA试剂盒进行双盲式同步测定,二法检验结果差异无显著性。渗滤法简便快速,适用于各级医院,有很强的推广价值。 相似文献
52.
苯DNA加合物研究进展(综述)李桂兰,常平综述徐伯洪审校(中国预防医学科学院劳动卫生与职业病研究所,北京100050)我国职业接触苯的工人约有50万,长期接触苯可引起白血病。苯与其它实质性肿瘤的问题也有报道[1,2]。世界癌症研究机构(IARC)19... 相似文献
53.
54.
A. A. Pal'tsyn O. A. Zakharova R. I. Kaem A. K. Badikova N. V. Chervonskaya 《Bulletin of experimental biology and medicine》1991,111(2):243-246
Department of Pathological Anatomy, A. V. Vishnevskii Institute of Surgery, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR D. S. Sarkisov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 111, No. 2, pp. 199–201, February, 1991. 相似文献
55.
Hans Brunner Thomas C Wetter Birgit Hogl Alexander Yassouridis Claudia Trenkwalder Elisabeth Friess 《Movement disorders》2002,17(5):928-933
We investigated non-rapid eye movement (non-REM) sleep in patients with newly diagnosed Parkinson's disease (PD) who had never previously received dopaminergic medication. There were no significant differences in the conventional sleep parameters between de novo patients with PD and a healthy control group, but the length of stage 1 sleep and the number of awakenings increased significantly upon administration of dopaminergic drugs. Analyzing the quantitative electroencephalogram (EEG), we observed a significant reduction in the low-delta frequency range and a nonsignificant increase in the sigma frequency range in de novo patients with PD. The dopaminergic medication also nonsignificantly reduced the low-delta and sigma frequencies, the latter to the level of the controls. Possible mechanisms that may account for the observed differences are discussed. It is suggested that Parkinson's disease as well as the application of dopaminergic drugs exerts a desynchronizing effect on the sleep EEG that is reflected in a disruption of sleep continuity. 相似文献
56.
油朝锋 《菏泽医学专科学校学报》2003,15(4):31-32
目的 研究非穿透性小梁切除术治疗开角型青光眼的手术效果。方法 对20例26眼开角型青光眼行非穿透性小梁切除术,术后观察眼压、结膜滤枕及前房反应等情况,随访1~12个月。结果 术后各期平均眼压均低于术前平均眼压,差异有显著性(P<0.05)术。前平均眼压26.26mmHg,术后3个月、6个月、9个月、12个月平均眼压分别为15.47mmHg、16.89mmHg、19.14mmHg、18.50mmHg。16眼结膜形成滤性手术典型滤过泡,10眼结膜疏松无滤过泡形成。26眼均无前房出血,术后前房反应轻。结论 非穿透性小梁切除术能有效地降低开角型青光眼的眼压,术后并发症少,可作为此类青光眼病人手术的选择。 相似文献
57.
58.
为了观察糖皮质激素对哮喘患者白细胞介素(IL)-5mRNA表达与嗜酸性粒细胞激活作用的影响,本研究用逆转录(RT)-聚合酶链反应(PCR)法半定量分析了哮喘患者用糖皮质激素治疗前后外周血单个核细胞(PBMC)中IL-5mRNA表达水平的变化,检测了血清嗜酸细胞阳离子蛋白(ECP)浓度、一秒钟用力呼气容积(FEV1)下降20%时的乙酰甲胆碱(MCH)激发浓度(MCH-PC20值)和基础FEV1占用力肺活量比值(FEV1%)等指标。结果发现,糖皮质激素不仅能改善哮喘患者的气道高反应性和通气功能,而且还可抑制PBMC中IL-5mRNA的表达和降低血清ECP浓度(P<0.05);血清ECP浓度下降幅度或MCH-PC20值改善幅度与IL-5mRNA表达水平下降幅度之间均呈显著正相关(r分别为0.5426和0.4857,P值<0.05)。提示糖皮质激素可能是通过抑制IL-5基因的转录,从而抑制后者对嗜酸性粒细胞的活化,而发挥其抗气道炎症反应和降低气道高反应性的作用。 相似文献
59.
Early erythroid precursors were studied in human bone marrow smears to provide more information on small proerythroblasts--"microproerythroblasts"--using a silver reaction to demonstrate silver stained nucleolar organizer regions (AgNORs) and light microscopic densitometry of large irregularly shaped nucleoli and cytoplasm stained for RNA. No significant differences were found for the density of such nucleoli and basophilic cytoplasm between characteristic large proerythroblasts with a nuclear diameter larger that 9 microm (K2 and K1 erythroblasts) and small proerythroblasts--"microproerythroblasts" representing a subpopulation of K1/2 erythroblasts (early basophilic erythroblasts), which are characterized by a smaller nuclear diameter. In addition, large irregularly shaped nucleoli of "microproerythroblasts" possessed numerous silver stained particles representing AgNORs similar to those of large proerythroblasts. The number of AgNORs in "microproerythroblasts" was slightly, but significantly, smaller than that in large characteristic proerythroblasts. 相似文献
60.
K. Nagamani Manisha Rani Vishnuvardhan Reddy Panduranga Rao Sushma Rajyalakshmi Sunitha Pakalapaty 《Indian journal of medical microbiology》2022,40(1):12-17
PurposeNoroviruses are common viral agents in acute diarrhea in all age groups worldwide. Norovirus has been classified into 10 genogroups, GI to GX with over 48 genotypes among them the GII.4 genotype has evolved over time with a clear pattern of periodic variant replacement. Immunity is strain or genotype specific with little or no protection conferred across genogroups. The present study was aimed to determine the epidemiology, prevalent genotypes of norovirus in children below five years of age in the Hyderabad region, India.MethodsThe stool samples and clinical data were collected from 458 children below 5 years of age comprising of cases with acute gastroenteritis (n ?= ?366) and a control group (n ?= ?92) admitted to the pediatric ward. All the samples were tested for Norovirus by ELISA and RT-PCR. Sequencing was done for predominant strains.Results10.3% (n ?= ?38) of cases and 3.2% (n ?= ?3) of the control group were found to be Norovirus positive. Predominant genotypes were GII-82.5% followed by GI-12.5%.ConclusionSequencing and Phylogenetic analyses of 20 GII.4 strains was done. All of the isolates are clustered away from published the GII.4 variants thus suggesting the appearance of a new variant. 相似文献